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xenophagy

Term Information

Accession
GO:0098792
Name
xenophagy
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents. Source: GOC:PARL, GOC:autophagy, PMID:25497060, GOC:pad, PMID:19802565, PMID:20159618
Comment
While making xenophagy a subclass of (macro)autophagy may seem to directly contradict the definition of autophagy (literally self eating), it is clear that the same pathway is involved as in macroautophagy that doesn't target foreign material: formation of double-membrane-bounded autophagosomes that enclose a region of cytoplasm for degradation.
History
See term history for GO:0098792 at QuickGO
Subset
None
Feedback
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Parents of xenophagy (GO:0098792)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
xenophagy [BFO:0000050 relation] BFO:0000050  defense response to other organism (GO:0098542)
xenophagy [is_a relation] is_a  selective autophagy (GO:0061912)
Children of xenophagy (GO:0098792)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of xenophagy (GO:1904415) [RO:0002211 relation] RO:0002211  xenophagy
positive regulation of xenophagy (GO:1904417) [RO:0002213 relation] RO:0002213  xenophagy
negative regulation of xenophagy (GO:1904416) [RO:0002212 relation] RO:0002212  xenophagy
None.