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Term Information

Accession
GO:0048292
Name
isotype switching to IgD isotypes
Ontology
biological_process
Synonyms
class switching to IgD isotypes, isotype switch recombination to IgD isotypes
Alternate IDs
None
Definition
The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus. Source: PMID:2113175, PMID:9186655, ISBN:0781735149, PMID:12370374
Comment
Note that this term is to be used only for gene products involved in the expression of IgD through recombinational switching into the vestigial switch region at the 5' end of the IgD gene segment, rather than gene products involved in the expression of IgD through alternative splicing mechanisms.
History
See term history for GO:0048292 at QuickGO
Subset
None
Feedback
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Parents of isotype switching to IgD isotypes (GO:0048292)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
isotype switching to IgD isotypes [is_a relation] is_a  isotype switching (GO:0045190)
Children of isotype switching to IgD isotypes (GO:0048292)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of isotype switching to IgD isotypes (GO:0048300) [RO:0002212 relation] RO:0002212  isotype switching to IgD isotypes
regulation of isotype switching to IgD isotypes (GO:0048299) [RO:0002211 relation] RO:0002211  isotype switching to IgD isotypes
positive regulation of isotype switching to IgD isotypes (GO:0048301) [RO:0002213 relation] RO:0002213  isotype switching to IgD isotypes
None.