Planteome: Term Details for "T-helper 1 cell differentiation" (GO:0045063)

Term Information

Accession: GO:0045063
Name: T-helper 1 cell differentiation
Ontology: biological_process
Synonyms: T-helper 1 cell development
Alternate IDs: None
Definition: The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. Source: CL:0000545, GOC:ebc
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History: See term history for GO:0045063 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to T-helper 1 cell differentiation.; Link to all direct and indirect annotations to T-helper 1 cell differentiation.; Link to all direct and indirect annotations download (limited to first 10,000) for T-helper 1 cell differentiation.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0008150 biological_process
GO:0009987 cellular process
GO:0032502 developmental process
GO:0048869 cellular developmental process
GO:0048856 anatomical structure development
GO:0030154 cell differentiation
GO:0048468 cell development
GO:0002376 immune system process
GO:0032501 multicellular organismal process
GO:0050896 response to stimulus
GO:0001775 cell activation
GO:0030097 hemopoiesis
GO:0002252 immune effector process
GO:0006955 immune response
GO:0002263 cell activation involved in immune response
GO:0045321 leukocyte activation
GO:0002521 leukocyte differentiation
GO:0002366 leukocyte activation involved in immune response
GO:0046649 lymphocyte activation
GO:1903131 mononuclear cell differentiation
GO:0002285 lymphocyte activation involved in immune response
GO:0030098 lymphocyte differentiation
GO:0042110 T cell activation
GO:0046631 alpha-beta T cell activation
GO:0002286 T cell activation involved in immune response
GO:0030217 T cell differentiation
GO:0002287 alpha-beta T cell activation involved in immune response
GO:0046632 alpha-beta T cell differentiation
GO:0035710 CD4-positive, alpha-beta T cell activation
GO:0002292 T cell differentiation involved in immune response
GO:0002250 adaptive immune response
GO:0002293 alpha-beta T cell differentiation involved in immune response
GO:0043367 CD4-positive, alpha-beta T cell differentiation
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response
GO:0042088 T-helper 1 type immune response
GO:0042093 T-helper cell differentiation
GO:0045063 T-helper 1 cell differentiation
GO:0045626 negative regulation of T-helper 1 cell differentiation
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045625 regulation of T-helper 1 cell differentiation
GO:0002296 T-helper 1 cell lineage commitment

Parents of T-helper 1 cell differentiation (GO:0045063)

subject	relation	object
T-helper 1 cell differentiation	is_a	T-helper cell differentiation (GO:0042093)
T-helper 1 cell differentiation	BFO:0000050	T-helper 1 type immune response (GO:0042088)

Children of T-helper 1 cell differentiation (GO:0045063)

subject	relation	object
T-helper 1 cell lineage commitment (GO:0002296)	BFO:0000050	T-helper 1 cell differentiation
positive regulation of T-helper 1 cell differentiation (GO:0045627)	RO:0002213	T-helper 1 cell differentiation
negative regulation of T-helper 1 cell differentiation (GO:0045626)	RO:0002212	T-helper 1 cell differentiation
regulation of T-helper 1 cell differentiation (GO:0045625)	RO:0002211	T-helper 1 cell differentiation

T-helper 1 cell differentiation

Term Information

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Parents of T-helper 1 cell differentiation (GO:0045063)

Children of T-helper 1 cell differentiation (GO:0045063)

None.