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T cell differentiation

Term Information

Accession
GO:0030217
Name
T cell differentiation
Ontology
biological_process
Synonyms
T lymphocyte differentiation, T-cell differentiation, T-lymphocyte differentiation, T cell development
Alternate IDs
GO:0042112, GO:0046652
Definition
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. Source: GO_REF:0000022, GOC:mah, GOC:jid
Comment
Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0030217 at QuickGO
Subset
None
Feedback
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Parents of T cell differentiation (GO:0030217)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
T cell differentiation [is_a relation] is_a  lymphocyte differentiation (GO:0030098)
T cell differentiation [is_a relation] is_a  T cell activation (GO:0042110)
Children of T cell differentiation (GO:0030217)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
extrathymic T cell differentiation (GO:0033078) [is_a relation] is_a  T cell differentiation
alpha-beta T cell differentiation (GO:0046632) [is_a relation] is_a  T cell differentiation
cytotoxic T cell differentiation (GO:0045065) [is_a relation] is_a  T cell differentiation
regulatory T cell differentiation (GO:0045066) [is_a relation] is_a  T cell differentiation
pro-T cell differentiation (GO:0002572) [BFO:0000050 relation] BFO:0000050  T cell differentiation
T cell differentiation in thymus (GO:0033077) [is_a relation] is_a  T cell differentiation
regulation of T cell differentiation (GO:0045580) [RO:0002211 relation] RO:0002211  T cell differentiation
somatic diversification of T cell receptor genes (GO:0002568) [BFO:0000050 relation] BFO:0000050  T cell differentiation
T cell differentiation involved in immune response (GO:0002292) [is_a relation] is_a  T cell differentiation
T cell selection (GO:0045058) [BFO:0000050 relation] BFO:0000050  T cell differentiation
negative regulation of T cell differentiation (GO:0045581) [RO:0002212 relation] RO:0002212  T cell differentiation
gamma-delta T cell differentiation (GO:0042492) [is_a relation] is_a  T cell differentiation
positive regulation of T cell differentiation (GO:0045582) [RO:0002213 relation] RO:0002213  T cell differentiation
T cell lineage commitment (GO:0002360) [BFO:0000050 relation] BFO:0000050  T cell differentiation
None.