Planteome: Term Details for "Notch receptor processing, ligand-dependent" (GO:0035333)

Accession: GO:0035333
Name: Notch receptor processing, ligand-dependent
Ontology: biological_process
Synonyms: Notch S2 cleavage, Notch S3 cleavage
Alternate IDs: None
Definition: The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD). Source: PMID:12651094, GOC:bf
Comment: None
History: See term history for GO:0035333 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to Notch receptor processing, ligand-dependent.; Link to all direct and indirect annotations to Notch receptor processing, ligand-dependent.; Link to all direct and indirect annotations download (limited to first 10,000) for Notch receptor processing, ligand-dependent.
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subject	relation	object
Notch receptor processing, ligand-dependent	BFO:0000050	Notch receptor processing (GO:0007220)
Notch receptor processing, ligand-dependent	BFO:0000050	Notch signaling pathway (GO:0007219)
Notch receptor processing, ligand-dependent	is_a	membrane protein intracellular domain proteolysis (GO:0031293)

This term has no children.

Notch receptor processing, ligand-dependent