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Term Information

Accession
GO:0007219
Name
Notch signaling pathway
Ontology
biological_process
Synonyms
N signaling pathway, N signalling pathway, Notch receptor signaling pathway, Notch receptor signalling pathway, Notch signalling pathway, Notch-receptor signaling pathway, Notch-receptor signalling pathway
Alternate IDs
GO:0030179
Definition
The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Source: GOC:signaling, GOC:go_curators
Comment
None
History
See term history for GO:0007219 at QuickGO
Subset
None
Feedback
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Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of Notch signaling pathway (GO:0007219)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Notch signaling pathway [is_a relation] is_a  cell surface receptor signaling pathway (GO:0007166)
Children of Notch signaling pathway (GO:0007219)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of Notch signaling pathway (GO:0008593) [RO:0002211 relation] RO:0002211  Notch signaling pathway
positive regulation of Notch signaling pathway (GO:0045747) [RO:0002213 relation] RO:0002213  Notch signaling pathway
Notch signaling pathway involved in forebrain neuron fate commitment (GO:0021880) [is_a relation] is_a  Notch signaling pathway
Notch signaling pathway involved in somitogenesis (GO:1902359) [is_a relation] is_a  Notch signaling pathway
Notch signaling pathway involved in camera-type eye photoreceptor fate commitment (GO:0060227) [is_a relation] is_a  Notch signaling pathway
positive regulation of transcription of Notch receptor target (GO:0007221) [BFO:0000050 relation] BFO:0000050  Notch signaling pathway
Notch signaling pathway involved in arterial endothelial cell fate commitment (GO:0060853) [is_a relation] is_a  Notch signaling pathway
Notch signaling pathway involved in heart induction (GO:0003137) [is_a relation] is_a  Notch signaling pathway
Notch signaling pathway involved in forebrain neuroblast division (GO:0021876) [is_a relation] is_a  Notch signaling pathway
negative regulation of Notch signaling pathway (GO:0045746) [RO:0002212 relation] RO:0002212  Notch signaling pathway
Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment (GO:2000796) [is_a relation] is_a  Notch signaling pathway
Notch receptor processing, ligand-dependent (GO:0035333) [BFO:0000050 relation] BFO:0000050  Notch signaling pathway
Notch signaling involved in heart development (GO:0061314) [is_a relation] is_a  Notch signaling pathway