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Term Information

Accession
GO:0007094
Name
mitotic spindle assembly checkpoint signaling
Ontology
biological_process
Synonyms
mitotic cell cycle spindle assembly checkpoint, mitotic checkpoint, mitotic spindle assembly checkpoint, mitotic spindle assembly checkpoint signalling, signal transduction involved in mitotic cell cycle spindle assembly checkpoint, signal transduction involved in mitotic spindle assembly checkpoint, signaling pathway involved in Dma1-dependent checkpoint, signaling pathway involved in SAC-independent checkpoint, signalling pathway involved in Dma1-dependent checkpoint, signalling pathway involved in SAC-independent checkpoint, Dma1-dependent checkpoint, Mad2-dependent checkpoint, SAC-independent checkpoint, signal transduction involved in Dma1-dependent checkpoint, signal transduction involved in SAC-independent checkpoint, signaling cascade involved in Dma1-dependent checkpoint, signaling cascade involved in SAC-independent checkpoint, signalling cascade involved in Dma1-dependent checkpoint, signalling cascade involved in SAC-independent checkpoint
Alternate IDs
GO:1902420, GO:0044810, GO:0072480
Definition
A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signalling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC). Source: PMID:12360190, GOC:mtg_cell_cycle
Comment
None
History
See term history for GO:0007094 at QuickGO
Subset
None
Feedback
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Parents of mitotic spindle assembly checkpoint signaling (GO:0007094)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic spindle assembly checkpoint signaling [BFO:0000050 relation] BFO:0000050  mitotic cell cycle (GO:0000278)
mitotic spindle assembly checkpoint signaling [is_a relation] is_a  negative regulation of mitotic metaphase/anaphase transition (GO:0045841)
mitotic spindle assembly checkpoint signaling [is_a relation] is_a  spindle assembly checkpoint signaling (GO:0071173)
mitotic spindle assembly checkpoint signaling [is_a relation] is_a  mitotic spindle checkpoint signaling (GO:0071174)
Children of mitotic spindle assembly checkpoint signaling (GO:0007094)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) [RO:0002211 relation] RO:0002211  mitotic spindle assembly checkpoint signaling
positive regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090267) [RO:0002213 relation] RO:0002213  mitotic spindle assembly checkpoint signaling
negative regulation of mitotic spindle assembly checkpoint signaling (GO:0140499) [RO:0002212 relation] RO:0002212  mitotic spindle assembly checkpoint signaling
None.