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Term Information

Accession
GO:0000075
Name
cell cycle checkpoint signaling
Ontology
biological_process
Synonyms
cell cycle checkpoint, signal transduction involved in G2/M transition checkpoint, signal transduction involved in cell cycle checkpoint, G1/S checkpoint, G1/S transition checkpoint, G2/M checkpoint, G2/M transition checkpoint
Alternate IDs
GO:0031576, GO:0072395, GO:0072407, GO:0071779, GO:0072404
Definition
A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction. Source: GOC:mtg_cell_cycle
Comment
This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.
History
See term history for GO:0000075 at QuickGO
Subset
gocheck_do_not_annotate
Feedback
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Parents of cell cycle checkpoint signaling (GO:0000075)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cell cycle checkpoint signaling [RO:0002212 relation] RO:0002212  cell cycle phase transition (GO:0044770)
cell cycle checkpoint signaling [is_a relation] is_a  negative regulation of cell cycle phase transition (GO:1901988)
cell cycle checkpoint signaling [is_a relation] is_a  intracellular signal transduction (GO:0035556)
Children of cell cycle checkpoint signaling (GO:0000075)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitotic cell cycle checkpoint signaling (GO:0007093) [is_a relation] is_a  cell cycle checkpoint signaling
DNA integrity checkpoint signaling (GO:0031570) [is_a relation] is_a  cell cycle checkpoint signaling
spindle checkpoint signaling (GO:0031577) [is_a relation] is_a  cell cycle checkpoint signaling
regulation of cell cycle checkpoint (GO:1901976) [RO:0002211 relation] RO:0002211  cell cycle checkpoint signaling
positive regulation of cell cycle checkpoint (GO:1901978) [RO:0002213 relation] RO:0002213  cell cycle checkpoint signaling
meiotic cell cycle checkpoint signaling (GO:0033313) [is_a relation] is_a  cell cycle checkpoint signaling
negative regulation of cell cycle checkpoint (GO:1901977) [RO:0002212 relation] RO:0002212  cell cycle checkpoint signaling