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Term Information

Accession
GO:0001865
Name
NK T cell differentiation
Ontology
biological_process
Synonyms
NK T lymphocyte differentiation, NK T-cell differentiation, NK T-lymphocyte differentiation, NKT cell differentiation, NT cell differentiation, natural T cell differentiation, natural killer T cell differentiation, NK T cell development
Alternate IDs
None
Definition
The process in which a precursor cell type acquires the specialized features of a NK T cell. Source: PMID:10704459, ISBN:0781735149, GOC:add
Comment
Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History
See term history for GO:0001865 at QuickGO
Subset
None
Feedback
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Parents of NK T cell differentiation (GO:0001865)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NK T cell differentiation [is_a relation] is_a  alpha-beta T cell differentiation (GO:0046632)
Children of NK T cell differentiation (GO:0001865)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of NK T cell differentiation (GO:0051136) [RO:0002211 relation] RO:0002211  NK T cell differentiation
negative regulation of NK T cell differentiation (GO:0051137) [RO:0002212 relation] RO:0002212  NK T cell differentiation
positive regulation of NK T cell differentiation (GO:0051138) [RO:0002213 relation] RO:0002213  NK T cell differentiation
NK T cell lineage commitment (GO:0002364) [BFO:0000050 relation] BFO:0000050  NK T cell differentiation
None.