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Term Information

Accession
GO:0000375
Name
RNA splicing, via transesterification reactions
Ontology
biological_process
Synonyms
RNA splicing factor activity, transesterification mechanism, pre-mRNA splicing factor activity, spliceosomal catalysis
Alternate IDs
GO:0031202, GO:0000385
Definition
Splicing of RNA via a series of two transesterification reactions. Source: GOC:krc
Comment
Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism.
History
See term history for GO:0000375 at QuickGO
Subset
goslim_pir
Feedback
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Parents of RNA splicing, via transesterification reactions (GO:0000375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA splicing, via transesterification reactions [is_a relation] is_a  RNA splicing (GO:0008380)
Children of RNA splicing, via transesterification reactions (GO:0000375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
first spliceosomal transesterification activity (GO:0000384) [BFO:0000050 relation] BFO:0000050  RNA splicing, via transesterification reactions
second spliceosomal transesterification activity (GO:0000386) [BFO:0000050 relation] BFO:0000050  RNA splicing, via transesterification reactions
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) [is_a relation] is_a  RNA splicing, via transesterification reactions
RNA splicing, via transesterification reactions with guanosine as nucleophile (GO:0000376) [is_a relation] is_a  RNA splicing, via transesterification reactions
None.