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Term Information

Accession
GO:1990926
Name
short-term synaptic potentiation
Ontology
biological_process
Synonyms
synaptic facilitation
Alternate IDs
None
Definition
The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds. Source: PMID:26738595, GOC:sp, PMID:11826273, ISBN:9780071120005, GOC:dos
Comment
The mechanism of short term potentiation is thought to be either increased influx of calcium into the presynapse (Zucker and Regeh, 2002 PMID:11826273) increased sensitivity to calcium (Jackman et al., 2016 PMID:26738595) or both.
History
See term history for GO:1990926 at QuickGO
Subset
None
Feedback
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Parents of short-term synaptic potentiation (GO:1990926)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
short-term synaptic potentiation [is_a relation] is_a  regulation of synaptic plasticity (GO:0048167)
Children of short-term synaptic potentiation (GO:1990926)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of short-term synaptic potentiation (GO:1905513) [RO:0002212 relation] RO:0002212  short-term synaptic potentiation
positive regulation of short-term synaptic potentiation (GO:1905514) [RO:0002213 relation] RO:0002213  short-term synaptic potentiation
regulation of short-term synaptic potentiation (GO:1905512) [RO:0002211 relation] RO:0002211  short-term synaptic potentiation
None.