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mutator focus

Term Information

Accession
GO:1990633
Name
mutator focus
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules. Source: PMID:22713602, PMID:25635455, GOC:kmv
Comment
None
History
See term history for GO:1990633 at QuickGO
Subset
None
Feedback
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Parents of mutator focus (GO:1990633)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mutator focus [is_a relation] is_a  cytoplasmic ribonucleoprotein granule (GO:0036464)
mutator focus [BFO:0000050 relation] BFO:0000050  perinuclear region of cytoplasm (GO:0048471)

This term has no children.

None.