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Dom34-Hbs1 complex
Term Information
Accession
GO:1990533
Name
Dom34-Hbs1 complex
Ontology
cellular_component
Synonyms
Dom34:Hbs1 complex
Alternate IDs
None
Definition
A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.
Source:PMID:20890290,
GOC:mcc,
PMID:22503425,
PMID:21102444,
PMID:21448132
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