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Term Information

Accession
GO:1990500
Name
eif4e-cup complex
Ontology
cellular_component
Synonyms
eukaryotic translation initiation factor 4E-cup complex
Alternate IDs
None
Definition
A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo. Source: PMID:14723848, GOC:bhm
Comment
An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction).
History
See term history for GO:1990500 at QuickGO
Subset
None
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Parents of eif4e-cup complex (GO:1990500)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
eif4e-cup complex [BFO:0000050 relation] BFO:0000050  P-body (GO:0000932)
eif4e-cup complex [is_a relation] is_a  translation repressor complex (GO:1903502)

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