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raps-insc complex

Term Information

Accession
GO:1990499
Name
raps-insc complex
Ontology
cellular_component
Synonyms
Rapsynoid-Inscuteable complex, partner of inscuteable-inscuteable complex
Alternate IDs
None
Definition
Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2). Source: PMID:22171003, GOC:bhm
Comment
An example of this is Insc in drome (Q9W2R4) in PMID:22171003 (inferred from physical interaction).
History
See term history for GO:1990499 at QuickGO
Subset
None
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Parents of raps-insc complex (GO:1990499)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
raps-insc complex [is_a relation] is_a  protein-containing complex (GO:0032991)
raps-insc complex [BFO:0000050 relation] BFO:0000050  apical cortex (GO:0045179)

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None.