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Rhino-Deadlock-Cutoff Complex

Term Information

Accession
GO:1990469
Name
Rhino-Deadlock-Cutoff Complex
Ontology
cellular_component
Synonyms
RDC complex, rhi-del-cuff complex
Alternate IDs
None
Definition
Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation. Source: PMID:24906153, GOC:bhm
Comment
An example of this is cuff in Drosophila melanogaster (Q9V629) in PMID:24906153.
History
See term history for GO:1990469 at QuickGO
Subset
None
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Parents of Rhino-Deadlock-Cutoff Complex (GO:1990469)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Rhino-Deadlock-Cutoff Complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
Rhino-Deadlock-Cutoff Complex [BFO:0000050 relation] BFO:0000050  germ cell nucleus (GO:0043073)
Rhino-Deadlock-Cutoff Complex [is_a relation] is_a  PET complex (GO:1990923)

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None.