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EFF-1 complex

Term Information

Accession
GO:1990392
Name
EFF-1 complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer. Source: PMID:24725407, GOC:bhm
Comment
An example of this is eff-1 in C. elegans (G5ECA1) in PMID:24725407 (inferred from direct assay).
History
See term history for GO:1990392 at QuickGO
Subset
None
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Parents of EFF-1 complex (GO:1990392)
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EFF-1 complex [is_a relation] is_a  plasma membrane protein complex (GO:0098797)

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None.