Planteome: Term Details for "UBR1-RAD6 ubiquitin ligase complex" (GO:1990303)

Accession: GO:1990303
Name: UBR1-RAD6 ubiquitin ligase complex
Ontology: cellular_component
Synonyms: UBR1-RAD6 complex
Alternate IDs: None
Definition: A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes. Source: PMID:19531475, GOC:bhm
Comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).
History: See term history for GO:1990303 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to UBR1-RAD6 ubiquitin ligase complex.; Link to all direct and indirect annotations to UBR1-RAD6 ubiquitin ligase complex.; Link to all direct and indirect annotations download (limited to first 10,000) for UBR1-RAD6 ubiquitin ligase complex.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

subject	relation	object
UBR1-RAD6 ubiquitin ligase complex	is_a	intracellular protein-containing complex (GO:0140535)
UBR1-RAD6 ubiquitin ligase complex	is_a	transferase complex (GO:1990234)

This term has no children.

UBR1-RAD6 ubiquitin ligase complex