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Term Information

Accession
GO:1905908
Name
positive regulation of amyloid fibril formation
Ontology
biological_process
Synonyms
up regulation of amyloid fibril formation, up-regulation of amyloid fibril formation, upregulation of amyloid fibril formation, activation of amyloid fibril assembly, activation of amyloid structure assembly, activation of amyloid structure formation, positive regulation of amyloid fibril assembly, positive regulation of amyloid structure assembly, positive regulation of amyloid structure formation, up regulation of amyloid fibril assembly, up regulation of amyloid structure assembly, up regulation of amyloid structure formation, up-regulation of amyloid fibril assembly, up-regulation of amyloid structure assembly, up-regulation of amyloid structure formation, upregulation of amyloid fibril assembly, upregulation of amyloid structure assembly, upregulation of amyloid structure formation, activation of amyloid fibril formation
Alternate IDs
None
Definition
Any process that activates or increases the frequency, rate or extent of amyloid fibril formation. Source: PMID:23106396, GOC:TermGenie, GOC:bc, GO_REF:0000058, GOC:aruk
Comment
Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896).
History
See term history for GO:1905908 at QuickGO
Subset
None
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Parents of positive regulation of amyloid fibril formation (GO:1905908)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of amyloid fibril formation [is_a relation] is_a  positive regulation of supramolecular fiber organization (GO:1902905)
positive regulation of amyloid fibril formation [is_a relation] is_a  positive regulation of protein metabolic process (GO:0051247)
positive regulation of amyloid fibril formation [RO:0002213 relation] RO:0002213  amyloid fibril formation (GO:1990000)
positive regulation of amyloid fibril formation [is_a relation] is_a  regulation of amyloid fibril formation (GO:1905906)

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