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Term Information

Accession
GO:1902988
Name
neurofibrillary tangle assembly
Ontology
biological_process
Synonyms
neurofibrillary tangle formation, flame-shaped neurofibrillary tangle assembly, flame-shaped neurofibrillary tangle formation, star-shaped neurofibrillary tangle assembly, star-shaped neurofibrillary tangle formation
Alternate IDs
None
Definition
The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle. Source: GOC:sjp, PMID:22986780, GOC:TermGenie, PMID:15897157, GO_REF:0000079, PMID:24154541
Comment
Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267).
History
See term history for GO:1902988 at QuickGO
Subset
None
Feedback
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Parents of neurofibrillary tangle assembly (GO:1902988)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
neurofibrillary tangle assembly [is_a relation] is_a  inclusion body assembly (GO:0070841)
Children of neurofibrillary tangle assembly (GO:1902988)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of neurofibrillary tangle assembly (GO:1902996) [RO:0002211 relation] RO:0002211  neurofibrillary tangle assembly
positive regulation of neurofibrillary tangle assembly (GO:1902998) [RO:0002213 relation] RO:0002213  neurofibrillary tangle assembly
negative regulation of neurofibrillary tangle assembly (GO:1902997) [RO:0002212 relation] RO:0002212  neurofibrillary tangle assembly
None.