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nonsense-mediated decay complex
Term Information
Accession
GO:0170010
Name
nonsense-mediated decay complex
Ontology
cellular_component
Synonyms
Upf complex
Alternate IDs
None
Definition
A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
Source:
GOC:lnp,
PMID:29282598,
PMID:1569946,
PMID:9032286
Link
to all annotated objects annotated to nonsense-mediated decay complex.
Link
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Link
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for nonsense-mediated decay complex.
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