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multi-pass translocon complex

Term Information

Accession
GO:0160064
Name
multi-pass translocon complex
Ontology
cellular_component
Synonyms
MPT complex, TMCO1 translocon
Alternate IDs
None
Definition
A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47). Source: PMID:36261522, PMID:36261528
Comment
None
History
See term history for GO:0160064 at QuickGO
Subset
None
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Parents of multi-pass translocon complex (GO:0160064)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
multi-pass translocon complex [is_a relation] is_a  ER membrane insertion complex (GO:0072379)

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None.