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Cyc8(Ssn6)-Tup1 general repressor complex
Term Information
Accession
GO:0160051
Name
Cyc8(Ssn6)-Tup1 general repressor complex
Ontology
cellular_component
Synonyms
Tup11/Tup12 repressor complex
Alternate IDs
None
Definition
A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class I HDAC, and recruits the SWI/SNF and SAGA complexes to promoters.
Source:PMID:17101775,
GOC:vw,
PMID:22156212,
PMID:10871883
Link
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Link
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