You are using the Cyverse mirror of the Planteome Ontology Browser. The main site is currently down for maintenance.

Term Information

Accession
GO:0140627
Name
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
Ontology
biological_process
Synonyms
DesCEND
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. Source: PMID:29775578, PMID:29779948
Comment
None
History
See term history for GO:0140627 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (GO:0140627)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)

This term has no children.

None.