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Term Information

Accession
GO:0140616
Name
iodotyrosine deiodinase activity
Ontology
molecular_function
Synonyms
iodide peroxidase-tyrosine iodinase activity, iodotyrosine deiodase activity, monoiodotyrosine deiodinase activity, tyrosine iodinase activity
Alternate IDs
None
Definition
Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates. Source: PMID:25395621, PMID:27643701, PMID:15289438, RHEA:32479, PMID:18434651
Comment
None
History
See term history for GO:0140616 at QuickGO
Subset
None
Feedback
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Parents of iodotyrosine deiodinase activity (GO:0140616)
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iodotyrosine deiodinase activity [is_a relation] is_a  oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond (GO:0046992)

This term has no children.

EC
1.21.1.1
RHEA
32479