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CMG complex assembly
Term Information
Accession
GO:0140529
Name
CMG complex assembly
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes.
Source:PMID:28501329,
PMID:22718908
Link
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Link
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Link
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