Planteome: Term Details for "microlipophagy" (GO:0140504)

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Term Information

Accession: GO:0140504
Name: microlipophagy
Ontology: biological_process
Synonyms: lipid droplet autophagy
Alternate IDs: None
Definition: Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination. Source: PMID:29293450, PMID:25070953, PMID:29601311, PMID:28394250, PMID:28838958
Comment: None
History: See term history for GO:0140504 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to microlipophagy.; Link to all direct and indirect annotations to microlipophagy.; Link to all direct and indirect annotations download (limited to first 10,000) for microlipophagy.
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