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HRI-mediated signaling
Term Information
Accession
GO:0140468
Name
HRI-mediated signaling
Ontology
biological_process
Synonyms
EIF2AK1-mediated signaling
Alternate IDs
None
Definition
A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.
Source:PMID:27629041
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