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rixosome complex
Term Information
Accession
GO:0120330
Name
rixosome complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.
Source:PMID:32491985,
GOC:vw,
PMID:35355014
Link
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Link
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