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SHREC2 complex
Term Information
Accession
GO:0110129
Name
SHREC2 complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.
Source:PMID:19111658,
GOC:mah
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