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RNA polymerase II termination complex
Term Information
Accession
GO:0110103
Name
RNA polymerase II termination complex
Ontology
cellular_component
Synonyms
TXT complex
Alternate IDs
None
Definition
A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.
Source:PMID:25722373,
GOC:lnp,
PMID:23200120
Comment
In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1.
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