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viral genome circularization
Term Information
Accession
GO:0099009
Name
viral genome circularization
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities.
Source:PMID:15489417,
PMID:11894948,
VZ:3968,
PMID:19523475,
PMID:319596
Link
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Link
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