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fast, calcium ion-dependent exocytosis of neurotransmitter
Term Information
Accession
GO:0098746
Name
fast, calcium ion-dependent exocytosis of neurotransmitter
Ontology
biological_process
Synonyms
synchronous, calcium ion-dependent exocytosis of neurotransmitter
Alternate IDs
None
Definition
The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
Source:
GOC:PARL,
PMID:4405553,
PMID:7809151,
GOC:pad,
PMID:7954835,
GOC:dos
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