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serpin family protein binding
Term Information
Accession
GO:0097655
Name
serpin family protein binding
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.
Source:PMID:16737556,
GOC:mr,
InterPro:IPR000215
Link
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