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synaptic vesicle protein transport vesicle

Term Information

Accession
GO:0097547
Name
synaptic vesicle protein transport vesicle
Ontology
cellular_component
Synonyms
STV
Alternate IDs
None
Definition
A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon. Source: GOC:dr, PMID:21569270
Comment
This term should not be confused with GO:0008021 'synaptic vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.
History
See term history for GO:0097547 at QuickGO
Subset
None
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Parents of synaptic vesicle protein transport vesicle (GO:0097547)
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synaptic vesicle protein transport vesicle [is_a relation] is_a  cytoplasmic vesicle (GO:0031410)

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