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Rad6-Rad18 complex
Term Information
Accession
GO:0097505
Name
Rad6-Rad18 complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.
Source:PMID:9287349,
GOC:jd
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