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perinucleolar compartment
Term Information
Accession
GO:0097356
Name
perinucleolar compartment
Ontology
cellular_component
Synonyms
perinucleolar region
Alternate IDs
None
Definition
The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.
Source:
GOC:vw,
PMID:21385875,
Wikipedia:Perinucleolar_compartment
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