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centralspindlin complex
Term Information
Accession
GO:0097149
Name
centralspindlin complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
Source:PMID:16236794,
GOC:ans,
PMID:11782313
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