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Term Information

Accession
GO:0097136
Name
Bcl-2 family protein complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed. Source: GOC:so, PMID:14634621
Comment
None
History
See term history for GO:0097136 at QuickGO
Subset
None
Link to all annotated objects annotated to Bcl-2 family protein complex.
Link to all direct and indirect annotations to Bcl-2 family protein complex.
Link to all direct and indirect annotations download (limited to first 10,000) for Bcl-2 family protein complex.
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Parents of Bcl-2 family protein complex (GO:0097136)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Bcl-2 family protein complex [is_a relation] is_a  protein-containing complex (GO:0032991)
Children of Bcl-2 family protein complex (GO:0097136)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
BAD-BCL-2 complex (GO:0097138) [is_a relation] is_a  Bcl-2 family protein complex
BIM-BCL-2 complex (GO:0097141) [is_a relation] is_a  Bcl-2 family protein complex
BAK complex (GO:0097145) [is_a relation] is_a  Bcl-2 family protein complex
BID-BCL-2 complex (GO:0097139) [is_a relation] is_a  Bcl-2 family protein complex
NOXA-BCL-xl complex (GO:0097146) [is_a relation] is_a  Bcl-2 family protein complex
PUMA-BCL-2 complex (GO:0097142) [is_a relation] is_a  Bcl-2 family protein complex
NOXA-BCL-2 complex (GO:0097147) [is_a relation] is_a  Bcl-2 family protein complex
BAX complex (GO:0097144) [is_a relation] is_a  Bcl-2 family protein complex
BAD-BCL-xl complex (GO:0097137) [is_a relation] is_a  Bcl-2 family protein complex
BCL-2 complex (GO:0097148) [is_a relation] is_a  Bcl-2 family protein complex
BIM-BCL-xl complex (GO:0097140) [is_a relation] is_a  Bcl-2 family protein complex
PUMA-BCL-xl complex (GO:0097143) [is_a relation] is_a  Bcl-2 family protein complex
None.