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Term Information

Accession
GO:0090500
Name
endocardial cushion to mesenchymal transition
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Source: GOC:dph, GOC:tb
Comment
None
History
See term history for GO:0090500 at QuickGO
Subset
None
Feedback
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Parents of endocardial cushion to mesenchymal transition (GO:0090500)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
endocardial cushion to mesenchymal transition [is_a relation] is_a  cardiac epithelial to mesenchymal transition (GO:0060317)
Children of endocardial cushion to mesenchymal transition (GO:0090500)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of endocardial cushion to mesenchymal transition (GO:0140050) [RO:0002212 relation] RO:0002212  endocardial cushion to mesenchymal transition
endocardial cushion to mesenchymal transition involved in heart chamber septation (GO:0003200) [is_a relation] is_a  endocardial cushion to mesenchymal transition
endocardial cushion to mesenchymal transition involved in heart valve formation (GO:0003199) [is_a relation] is_a  endocardial cushion to mesenchymal transition
endocardial cushion to mesenchymal transition involved in cardiac skeleton development (GO:0003202) [is_a relation] is_a  endocardial cushion to mesenchymal transition
positive regulation of endocardial cushion to mesenchymal transition (GO:0140051) [RO:0002213 relation] RO:0002213  endocardial cushion to mesenchymal transition
regulation of endocardial cushion to mesenchymal transition (GO:0140049) [RO:0002211 relation] RO:0002211  endocardial cushion to mesenchymal transition
None.