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G-quadruplex DNA formation
Term Information
Accession
GO:0071919
Name
G-quadruplex DNA formation
Ontology
biological_process
Synonyms
G quadruplex DNA formation, G quartet DNA formation, G-quartet DNA formation
Alternate IDs
None
Definition
A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.
Source:PMID:20098422,
GOC:sre
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