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U2-type precatalytic spliceosome

Term Information

Accession
GO:0071005
Name
U2-type precatalytic spliceosome
Ontology
cellular_component
Synonyms
major precatalytic spliceosome, yeast U12-type spliceosomal complex A2-1, GT-AG precatalytic spliceosome, mammalian U2-type spliceosomal complex B, mammalian U2-type spliceosomal complex B1
Alternate IDs
None
Definition
A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs. Source: GOC:krc, PMID:19239890, GOC:ab, GOC:mah, PMID:18322460
Comment
None
History
See term history for GO:0071005 at QuickGO
Subset
None
Feedback
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Parents of U2-type precatalytic spliceosome (GO:0071005)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
U2-type precatalytic spliceosome [BFO:0000051 relation] BFO:0000051  U1 snRNP (GO:0005685)
U2-type precatalytic spliceosome [is_a relation] is_a  U2-type spliceosomal complex (GO:0005684)
U2-type precatalytic spliceosome [BFO:0000051 relation] BFO:0000051  U2 snRNP (GO:0005686)
U2-type precatalytic spliceosome [is_a relation] is_a  precatalytic spliceosome (GO:0071011)
U2-type precatalytic spliceosome [BFO:0000051 relation] BFO:0000051  U4/U6 x U5 tri-snRNP complex (GO:0046540)

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None.