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Term Information

Accession
GO:0070822
Name
Sin3-type complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex. Source: PMID:15565322, PMID:18292778
Comment
None
History
See term history for GO:0070822 at QuickGO
Subset
None
Feedback
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Parents of Sin3-type complex (GO:0070822)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Sin3-type complex [BFO:0000050 relation] BFO:0000050  nuclear chromosome (GO:0000228)
Sin3-type complex [BFO:0000050 relation] BFO:0000050  chromatin (GO:0000785)
Sin3-type complex [is_a relation] is_a  histone deacetylase complex (GO:0000118)
Children of Sin3-type complex (GO:0070822)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Rpd3S complex (GO:0032221) [is_a relation] is_a  Sin3-type complex
Rpd3L complex (GO:0033698) [is_a relation] is_a  Sin3-type complex
Sin3 complex (GO:0016580) [is_a relation] is_a  Sin3-type complex
None.