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interleukin-27 complex
Term Information
Accession
GO:0070744
Name
interleukin-27 complex
Ontology
cellular_component
Synonyms
IL-27 complex, EBI3, IL27, p28
Alternate IDs
None
Definition
A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
Source:
GOC:add,
PMID:15999093,
PMID:19161428
Comment
Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits.
Link
to all annotated objects annotated to interleukin-27 complex.
Link
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to interleukin-27 complex.
Link
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for interleukin-27 complex.
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