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Term Information

Accession
GO:0070685
Name
macropinocytic cup
Ontology
cellular_component
Synonyms
crown
Alternate IDs
None
Definition
A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin. Source: PMID:12538772, PMID:9044041, PMID:16968738
Comment
None
History
See term history for GO:0070685 at QuickGO
Subset
None
Feedback
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Parents of macropinocytic cup (GO:0070685)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
macropinocytic cup [is_a relation] is_a  plasma membrane bounded cell projection (GO:0120025)
Children of macropinocytic cup (GO:0070685)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
macropinocytic cup membrane (GO:0070686) [BFO:0000050 relation] BFO:0000050  macropinocytic cup
macropinocytic cup cytoskeleton (GO:0070687) [BFO:0000050 relation] BFO:0000050  macropinocytic cup
None.