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Term Information

Accession
GO:0070449
Name
elongin complex
Ontology
cellular_component
Synonyms
elongin (SIII) complex, transcription elongation factor SIII complex, transcription factor B (SIII) complex
Alternate IDs
None
Definition
A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits. Source: PMID:12676794
Comment
See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
History
See term history for GO:0070449 at QuickGO
Subset
None
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Parents of elongin complex (GO:0070449)
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elongin complex [is_a relation] is_a  transcription elongation factor complex (GO:0008023)

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