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ERK5 cascade

Term Information

Accession
GO:0070375
Name
ERK5 cascade
Ontology
biological_process
Synonyms
BMK cascade, BMK signaling pathway, BMK signalling pathway, BMK1 cascade, ERK5 signaling pathway, MAPK7 cascade, big MAP kinase signaling cascade, extracellular signal-regulated kinase 5 cascade
Alternate IDs
None
Definition
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. Source: GOC:signaling, ISBN:0896039986, PMID:20811974, PMID:28903453, PMID:16880823, GOC:add, PMID:16376520
Comment
None
History
See term history for GO:0070375 at QuickGO
Subset
None
Feedback
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Parents of ERK5 cascade (GO:0070375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ERK5 cascade [is_a relation] is_a  MAPK cascade (GO:0000165)
Children of ERK5 cascade (GO:0070375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of ERK5 cascade (GO:0070377) [RO:0002212 relation] RO:0002212  ERK5 cascade
positive regulation of ERK5 cascade (GO:0070378) [RO:0002213 relation] RO:0002213  ERK5 cascade
regulation of ERK5 cascade (GO:0070376) [RO:0002211 relation] RO:0002211  ERK5 cascade
None.