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obsolete necrotic cell death
Obsolete Term Information
Accession
GO:0070265
Name
obsolete necrotic cell death
Ontology
biological_process
Synonyms
cellular necrosis, necrosis
Alternate IDs
None
Definition
OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.
Source:PMID:20823910,
GOC:mtg_apoptosis,
PMID:18846107
Comment
The reason for obsoletion is that this term represent an assay and not a GO process.
The reason for obsoletion is that this represents a phenotype.
Link
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Link
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Link
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