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telomeric DNA-containing double minutes formation
Term Information
Accession
GO:0061819
Name
telomeric DNA-containing double minutes formation
Ontology
biological_process
Synonyms
TDMs formation
Alternate IDs
None
Definition
A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.
Source:
GOC:BHF_telomere,
GOC:BHF,
PMID:14690602,
GOC:nc,
PMID:2397458
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