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canonical Wnt signaling pathway

Term Information

Accession
GO:0060070
Name
canonical Wnt signaling pathway
Ontology
biological_process
Synonyms
Wnt receptor signaling pathway through beta-catenin, Wnt receptor signaling pathway via beta-catenin, Wnt receptor signalling pathway through beta-catenin, canonical Wnt receptor signaling pathway, canonical Wnt-activated signaling pathway, frizzled-1 receptor signaling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. Source: GOC:dph, PMID:11532397, PMID:19619488, GOC:bf
Comment
None
History
See term history for GO:0060070 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of canonical Wnt signaling pathway (GO:0060070)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
canonical Wnt signaling pathway [is_a relation] is_a  Wnt signaling pathway (GO:0016055)
Children of canonical Wnt signaling pathway (GO:0060070)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation (GO:0060823) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in regulation of cell proliferation (GO:0044340) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in osteoblast differentiation (GO:0044339) [is_a relation] is_a  canonical Wnt signaling pathway
beta-catenin destruction complex disassembly (GO:1904886) [BFO:0000050 relation] BFO:0000050  canonical Wnt signaling pathway
regulation of hair cycle by canonical Wnt signaling pathway (GO:0060901) [is_a relation] is_a  canonical Wnt signaling pathway
receptor internalization involved in canonical Wnt signaling pathway (GO:2000286) [BFO:0000050 relation] BFO:0000050  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in metanephric kidney development (GO:0061290) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation (GO:0044338) [is_a relation] is_a  canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway (GO:0090090) [RO:0002212 relation] RO:0002212  canonical Wnt signaling pathway
regulation of canonical Wnt signaling pathway (GO:0060828) [RO:0002211 relation] RO:0002211  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in negative regulation of apoptotic process (GO:0044336) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation (GO:1904954) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion (GO:0044329) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition (GO:0044334) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in mesonephros development (GO:0061292) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in neural crest cell differentiation (GO:0044335) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration (GO:0044328) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in heart development (GO:0061316) [is_a relation] is_a  canonical Wnt signaling pathway
coreceptor activity involved in canonical Wnt signaling pathway (GO:1904928) [BFO:0000050 relation] BFO:0000050  canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway (GO:0090263) [RO:0002213 relation] RO:0002213  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in positive regulation of apoptotic process (GO:0044337) [is_a relation] is_a  canonical Wnt signaling pathway
positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway (GO:0100067) [is_a relation] is_a  canonical Wnt signaling pathway
regulation of heart induction by canonical Wnt signaling pathway (GO:0100012) [is_a relation] is_a  canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in positive regulation of wound healing (GO:0044330) [is_a relation] is_a  canonical Wnt signaling pathway
None.